• Register
  • Login

European Journal of Molecular & Clinical Medicine

  • Home
  • Browse
    • Current Issue
    • By Issue
    • By Subject
    • Keyword Index
    • Author Index
    • Indexing Databases XML
  • Journal Info
    • About Journal
    • Aims and Scope
    • Editorial Board
    • Publication Ethics
    • Indexing and Abstracting
    • Peer Review Process
    • News
  • Guide for Authors
  • Submit Manuscript
  • Contact Us
Advanced Search

Notice

As part of Open Journals’ initiatives, we create website for scholarly open access journals. If you are responsible for this journal and would like to know more about how to use the editorial system, please visit our website at https://ejournalplus.com or
send us an email to info@ejournalplus.com

We will contact you soon

  1. Home
  2. Volume 9, Issue 3
  3. Author

Online ISSN: 2515-8260

Volume9, Issue3

ClinicalStudy ofBacteriologicalPatterns andAntibiotic Sensitivity in Secondary Peritonitis

    Naveen Banoth, Venkatesh A

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 2461-2472

  • Show Article
  • Download
  • Cite
  • Statistics
  • Share

Abstract

Background:Intra-abdominal infections have been treated with various antibiotic regimens. These infections have been treated with single-agent and combination treatments. But no one therapy has been proven superior. The study's main goal is to examine the bacterial patterns in peritoneal fluid from surgical peritonitis patients and assess their antibiotic sensitivity and resistance.
Materials and Methods: It is a cross sectional observation research conducted in January 2020 to May 2021 which was conducted in JSS Hospital Mysuru. Analyzed data was in rates, proportions, and percentages. The sample includes 100 cases of secondary peritonitis caused by hollow viscus perforation, where preoperative peritoneal fluid samples were analysed for bacterial culture and sensitivity.
Results: Out of 100 samples, 50 had bacterial growth. The most common bacteria were E. coli. These were Acinobacter (6%), Candida (4%), Citrobacter (1%), Klebsiella (11%) and Serratia (2%). (4 percent). 77.5 percent of E. coli were sensitive to Ceftriaxone, 75% to Piperacillin-tazobactam, and 99.1 percent to Meropenem. In 40% of cases, E.coli was multidrug resistant. Most Klebsiellapneumoniae were responsive to ceftriaxone, piperacillin-tazobactam, and meropenem. Ciprofloxacin, Ceftriaxone, and Meropenem were all sensitive to Proteus mirabilis. 25.2 percent of cases were multidrug resistant bacteria.
Conclusion: The results of this investigation identify the organisms usually isolated from peritoneal fluid, their susceptibility and resistance to broad spectrum antibiotics. It shows the common gramme negative isolates and the current antibiotic resistance concern in these individuals. The most common microorganism found in gastrointestinal perforations is Escherichia coli. In most cases, numerous gramme negative bacilli develop polymicrobially. Antibiotic-resistant microorganisms, notably multidrug resistant Escherichia coli, are increasing in number. Third generation cephalosporins are becoming more resistant. In multidrug resistant organisms, Meropenem and Tigecycline seem to be the best options.
Keywords:
    Secondary Peritonitis Peritoneal fluid Culture and Sensitivity Escherichia coli Multi drug resistance
  • PDF (378 K)
  • XML
(2022). ClinicalStudy ofBacteriologicalPatterns andAntibiotic Sensitivity in Secondary Peritonitis. European Journal of Molecular & Clinical Medicine, 9(3), 2461-2472.
Naveen Banoth, Venkatesh A. "ClinicalStudy ofBacteriologicalPatterns andAntibiotic Sensitivity in Secondary Peritonitis". European Journal of Molecular & Clinical Medicine, 9, 3, 2022, 2461-2472.
(2022). 'ClinicalStudy ofBacteriologicalPatterns andAntibiotic Sensitivity in Secondary Peritonitis', European Journal of Molecular & Clinical Medicine, 9(3), pp. 2461-2472.
ClinicalStudy ofBacteriologicalPatterns andAntibiotic Sensitivity in Secondary Peritonitis. European Journal of Molecular & Clinical Medicine, 2022; 9(3): 2461-2472.
  • RIS
  • EndNote
  • BibTeX
  • APA
  • MLA
  • Harvard
  • Vancouver
  • Article View: 66
  • PDF Download: 96
  • LinkedIn
  • Twitter
  • Facebook
  • Google
  • Telegram
Journal Information

Publisher:

Email:  editor.ejmcm21@gmail.com

  • Home
  • Glossary
  • News
  • Aims and Scope
  • Privacy Policy
  • Sitemap

 

For Special Issue Proposal : editor.ejmcm21@gmail.com

This journal is licensed under a Creative Commons Attribution 4.0 International (CC-BY 4.0)

Powered by eJournalPlus