Evaluation Of Therapeutic Efficacy of Two Different Combinations of Local Anaesthetics: Ropivacaine‑Fentanyl Versus Bupivacaine‑Fentanyl In Lower Limb Orthopaedic Surgeries – A Randomised Controlled Trial
European Journal of Molecular & Clinical Medicine,
2021, Volume 8, Issue 4, Pages 2871-2877
AbstractBackground: Spinal anaesthesia is the most commonly performed anaesthetic technique. It has many advantages over general anaesthesia, such as a reduced stress response and better pain relief after surgery. Spinal bupivacaine causes a long-lasting block of movement and delays home discharge after ambulatory surgery. The aim of the present study was to evaluate the therapeutic efficacy of two different combinations of anaesthetics like ropivacaine‑fentanyl and bupivacaine‑fentanyl and also to note the adverse drug reactions in the two groups.
Materials and methods: The study was done with 40 people over a period of 8 months. They were split into two groups of 20 patients each by a computer randomization table. Group B received 3 ml (15 mg) of 0.5% bupivacaine with 25 mcg fentanyl and Group R received 3 ml of (15mg) of 0.5% ropivacaine with 25 mcg fentanyl. Hemodynamic parameters, sensory and motor block characteristics and adverse effects were noted in both the groups.
Results: There was no significant difference in both the groups with regard to hemodynamic parameters. Regression of motor block was earlier in ropivacaine group and the duration of analgesia was longer in bupivacaine group.
Conclusion: As ropivacaine is providing very shorter period of motor and sensory block in comparison with bupivacaine, it is more beneficial for the patients and it decreases the time of non-ambulatory phase.
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