Detection of abnormal haemoglobin variants and its characterization among anaemicsby high performance liquid chromatography (HPLC): A prospective study from North India
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 3, Pages 2552-2561
Abstract
Background: Hemoglobinopathies are one of the most common inherited blood illnessesin India and are one of the country's most serious public health issues. In India, it is
estimated that there are approximately 45 million carriers and 15,000 babies born with
hemoglobinopathies per year. The carrier rate of hemoglobinopathy in various Indian
demographic groups ranges from 3 to 17 percent. Automated cation-exchange High
Performance Liquid Chromatography (HPLC) has surfaced as an outstanding
screening tool for identifying this abnormal hemoglobin or thalassemic conditions. So,
the purpose of this study was to identify common haemoglobin disorders, in anaemia
patients using HPLC.
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