European Journal of Molecular & Clinical Medicine

Abstract

Aim & objective:Maternal and Perinatal Outcome in Hypothyroidism in preganacy at tertiary care center.
Materials & Methods:A prospective observational study conducted in the Department of Obstetrics & Gynaecology a tertiary care hospital in Aurangabad district of Maharashtra from September 2020  to September 2021. All patients who fulfilled the inclusion and exclusion criteria during the study period were included in the study.
Observation & Results: In the present studymajority of pregnant women 63 (38.4%) belonged to the age group of 21-25 years & majority 69(42.1%) of them were nulliparous. The risk factors identified in majority 20 (12.19%) of women was h/o pre-eclampsia and in 12 (7.31%) cases previous preterm delivery was observed as risk factor. Further it revealed that, there was statistically significant association between GA and raised TSH level (p<0.05). Maternal complications such as anaemia, severe pre-eclampsia and abruptio placenta were significantly correlated with high TSH level. It was observed that maternal and fetal outcome were significantly associated with level of TSH at the time of delivery.
Conclusion: The study concluded that timely diagnosis and management of thyroid dysfunction is the key to avoid obstetric complications. Supplementing thyroxin in patients with hypothyroidism can prevent maternal and fetal complication, so routine screening of thyroid dysfunction is recommended in pregnant women.