Abstract

Background:Pancytopenia is decrease in all the cellular constituents of the peripheral blood resulting in anaemia, leukopenia, and thrombocytopenia. Pancytopenia is characterised by anaemia, bleeding, and infection. The causes of pancytopenia vary widely. Hence, the present study was conducted to assess the profile of pancytopenia and its various causes.
Materials and Methods: The present cross-sectional observational study was conducted in Department of Pathology of a medical college hospital. A total of 40 cases of anaemia suffering from pancytopenia were included. Detailed history, clinical examination and investigations were done to determine the cause of pancytopenia.
Results: Most of the patients belonged to the age group of 21-30 years (37.5%). 57.5% were males. Megaloblastic anaemia was seen in 57.5% cases, hypoplastic/aplastic anaemia in 17.5% and hyersplenism in 7.5%.
Conclusion: Megaloblastic anaemia and aplastic anaemia were major causes of pancytopenia. Proper investigation is must in patients of pancytopenia