European Journal of Molecular & Clinical Medicine

Abstract

Background : Serum Uric Acid at it increased level is major concerned or risk factor for acute stroke patients and use of increased level of  serum  uric acid as marker of acute ischaemic stroke has debated issue according to some studies conducted in past. Thus we have undertaken this study to know how serum uric acid plays the role among Acute ischemic stroke patients. Materials and Methodology : This is prospective study conducted on 60 cases of divided into 30 cases (acute ischemic stroke) 30 controls. It was conducted in the department of Medicine at Government Medical College, Siddipet, Telangana State. A detailed history and thorough clinical examination was carried out in each patient.  Risk factors for stroke were noted such as hypertension, diabetes mellitus, smoking, and obesity. Serum uric acid levels were measured in cases and controls. Statistical analysis was performed with of SPSS 25 version software. Results : Among 60 patients of study population 39, were male and 21 were female. , mean age of patients from cases was 58.23 ± 7.32 years and that of in controls was 59.12 ± 8.23 Years. Hypertension and obesity was statistically significant among cases. mean serum uric acid level in  cases was 6.85 ± 2.1 mg/dl and that of in controls was 5.42 ± 1.42 mg/dl and it was statistically significant. There was statistically significant difference in mean serum uric acid level in hypertensive and obese patients compared to non hypertensive and non obese. Conclusion : Increased level of SUA significantly associated with acute phase of an Ischemic stroke.