ASSESSING THE CORRELATION BETWEEN THYROID PROFILE AND CLINICAL DIAGNOSIS IN SUBJECTS WITH MULTINODULAR GOITER
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 3, Pages 3105-3108
Abstract
Background: In endocrinology, the most commonly prevalent and undiagnosed condition encountered is thyroid dysfunction having a high burden on the healthcare sector in India. In addition, Iodine is an essential micronutrient for mental and physical growth in humans, its deficiency remains highly prevalent globally. Thyroid enlargement is commonly associated with thyroid deficiency clinically with decreased iron and selenium levels, and an increase in smoking, natural goitrogen, and TSH levels. Goiter representing enlargement of the entire thyroid gland is seen associated with raised levels of TSH, hyperthyroidism, or hypothyroidism.Aim: The present clinical study was conducted to assess the association of thyroid hormone levels and goiter by assessing the thyroid profile in subjects with goiter.
Methods:The present cross-sectional study included 200 subjects comprising of 100 subjects with goiter and 100 normal healthy subjects in the age range of 18-35 years. For all the included subjects, thyroid hormone profile and thyroid function tests were assessed.
Results:The study results showed a significant difference between healthy subjects and subjects with goiter in hyperthyroid and hypothyroid subjects. The prevalence of goiter was largely influenced by lower and higher concentrations of TSH.
Conclusion:The present study concludes that the prevalence of goiter largely depends on abnormal and normal levels of Thyroid Stimulating Hormone (TSH) depicting hormonal dysfunction. TSH levels, thyroid nodules, and female gender were found to be the possible predictor for goiter, whereas, thyroid volume, TSH levels, and female gender were found to be predictors for thyroid nodules. Assessment of epidemiological profile is needed to obtain the definitive conclusion.
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