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  2. Volume 9, Issue 3
  3. Author

Online ISSN: 2515-8260

Volume9, Issue3

A Prospective Study Evaluating the Correlation of Sleep Pattern, Melatonin Secretion and Obesity

    Annie Sandhu1, Dharminder Singh2, Akashdeep Singh2, Kuldip Singh Sandhu3, Savvy Aujla4 .

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 3174-3180

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Abstract

Background: The present study aims to assess correlation of sleep patterns, melatonin secretion, and obesity.
Materials and Methods: One hundred and twenty-two subjects in age ranged 11-17 years of both genders were subjected to fasting blood glucose, insulin level, uric acid, lipid profile and renal function test measurement. Insulin resistance and level of melatonin with enzyme-linked immunosorbent assay (ELISA) were determined.
Results: There were 30 males and 22 females without insulin resistance (IR) and 40 males and 30 females with IR. There were 6 prepubertal, 12 pubertal, and 34 postpubertal subjects without IR and 8 prepubertal, 15 pubertal, and 47 postpubertal subjects with IR. The mean Body Mass Index (BMI) (Kg/m2) was 29.1 and 34.2, Systolic Blood Pressure (SBP) (mm Hg) was 128.6 and 134.2, Diastolic Blood Pressure (DBP) (mm Hg) was 66 and 72, total cholesterol (TC) (mg/dl) was 160.2 and 164.8, triglyceride (TG) (mg/dl) was 70 and 104.2, High Density Lipoprotein (HDL) (mg/dl) cholesterol was 54.2 and 46.8 and Low-density lipoprotein (LDL) (mg/dl) cholesterol was 92 and 98 in subjects without IR and in subjects with IR respectively. The mean uric acid was 5.3 mg/dl in subjects without IR and 5.9 mg/dl in subjects with IR. The mean MT6s:Cr (Melatonin 6s: Creatinine) ratio was 31.4 in subjects without IR and 27.4 in subjects with IR. The difference between both groups was found to be significant (P< 0.05).
Keywords:
    Sleep Obesity melatonin
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(2022). A Prospective Study Evaluating the Correlation of Sleep Pattern, Melatonin Secretion and Obesity. European Journal of Molecular & Clinical Medicine, 9(3), 3174-3180.
Annie Sandhu1, Dharminder Singh2, Akashdeep Singh2, Kuldip Singh Sandhu3, Savvy Aujla4 .. "A Prospective Study Evaluating the Correlation of Sleep Pattern, Melatonin Secretion and Obesity". European Journal of Molecular & Clinical Medicine, 9, 3, 2022, 3174-3180.
(2022). 'A Prospective Study Evaluating the Correlation of Sleep Pattern, Melatonin Secretion and Obesity', European Journal of Molecular & Clinical Medicine, 9(3), pp. 3174-3180.
A Prospective Study Evaluating the Correlation of Sleep Pattern, Melatonin Secretion and Obesity. European Journal of Molecular & Clinical Medicine, 2022; 9(3): 3174-3180.
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