European Journal of Molecular & Clinical Medicine

Abstract

The autonomic nervous system, which is divided into sympathetic and parasympathetic divisions, plays a vital role in cardiovascular regulation. It has been demonstrated that heart rate variability can provide an objective measure of autonomic function. The Peripheral Pulse Analyzer has been used to research heart rate variability in healthy and hypertensive people in order to better understand the effects of hypertension on autonomic activity. Subjects were separated into two age groups: 18-30 years and 31-44 years, and variability factors were compared in terms of gender, age, and disease stratification. Statistical analysis revealed a significant reduction in the coefficient of variation for the variability parameter represented as a logarithm (to the base 10) in contrast to the raw or average value of the parameter, resulting in greater discriminatory strength in various stratified groups. Excluding age and gender sensitive factors, there is a significant difference in the amplitude of the low frequency component for lower age group male/female hypertensives and the amplitude and area of the low frequency component for higher age group female hypertensives. These findings are consistent with earlier research of a comparable scope. However, higher age group male controls and hypertensives could not be distinguished by variability study, most likely because to comparable changes indicated by senility and hypertension. As a result, the amplitude and area of the low frequency component in the heart rate variability spectrum have been identified as hypertension-specific parameters