European Journal of Molecular & Clinical Medicine

Abstract

Aims and objectives: To study the role of MR spectroscopy in the evaluation of various
ring enhancing lesions in the brain with single and multi-voxel proton MR
spectroscopy.Ring enhancing lesions represent an important public health challenge
and is a major cause of morbidity and mortality throughout the world.
Materials and methods: 100 cases referred to the Department of Radiodiagnosis and
Imaging, Government Medical College, Amritsar with clinically suspected brain lesions
were evaluated and statistically analyzed.
Results: Hundred patients with ring enhancing lesions were evaluated using MRI and
MR spectroscopy. Various parameters of ring enhancing lesions were evaluated and the
spectrum of findings on MRI and MRS were assessed. The patients were followed up
for clinical improvement based on the line of treatment. Few cases requiring
histopathological correlation were followed up based on biopsy reports and post
operative histopathological reports.
Conclusions: Conventional MRI is a great tool in making a sufficient differential
diagnosis of the ring enhancing lesions of the brain, but MR spectroscopy further helps
in knowing the chemical nature of lesions and accurate diagnosis of brain tumours. This
facilitates the clinician to plan the best line of treatment thus reducing the suffering and
morbidity of the patients.