Abstract

Aim: Evaluation of serum levels of Vitamin D and contrast effects and controls in vitiligo
patients.
Methods: After receiving ethical approval from management, this case control research was
conducted in the department of dermatology. This study comprised 100 clinically diagnosed
instances of dermatological vitiligo (group A) and 100 control (group B) participants. The
control group (Group B) was made up of age and gender matched healthy volunteers. A
history of thyroid dysfunction, atopy, and diabetes was also suggested. Participants in the
research were all subjected to a complete general physical examination. A full systematic
study for associated disorders was also performed, and the results were recorded. A full
cutaneous investigation, including mucosa, was performed to diagnose the disease, determine
the type of the vitiligo, and investigate specific features such as trichrome, quadrichrome, and
leukotrichia.
Results: In our study, 200 patients who satisfied the inclusion criteria were enrolled, with
100 in Group A and 100 in Group B. The majority of patients (35.5 percent) were between
the ages of 30 and 40, with 34.5 percent between the ages of 40 and 50. 16.5 percent of the
patients were above the age of 30. Around 13.5 percent of those polled were above the age of
50. Males made up 54 percent of our research subjects, while females made up 46 percent.
Vulgaris was the most common kind of vitiligo observed in 50 percent of the cases. Mucosal
Vitiligo was seen in 13% of the patients. Both segmental and focal vitiligo were observed in
10% of the patients. AcrofacialVitiligo was seen in 11% of the patients, whereas Universalis
was seen in 7% of the cases. The duration of Vitiligo was less than 6 years in 70% of the
patients. In 21% of instances, the duration of vitiligo ranged from 6 to 12 years. In 7% of
instances, the duration of vitiligo ranged from 12 to 18 years and from 18 to 24 years. In 5%
of individuals, the vitiligo had been present for more than 24 years.
Conclusion: This analysis is closely linked to serum cholecalciferol and vitiligo.
Cholecalciferol is also strongly linked to the clinical type, duration, and severity of vitiligo.
Our research highlights the importance of low vitamin D levels in the aetiology of vitiligo, as
well as the function of vitamin D supplementation in the therapy of vitiligo.