European Journal of Molecular & Clinical Medicine

Abstract

Background:The present study was conducted for assessing patients of transplant kidney
with magnetic resonance imaging.
Materials & methods: A total of 20 patients with undergoing renal transplant were enrolled.
Complete demographic and clinical details of all the patients were assessed. The composite
data was tabulated and studied to evaluate the feasibility of functional MRI parameters i.e.
the blood oxygen level dependent (BOLD-based R2* values), in order to establish role of
functional MRI as one of the reliable noninvasive diagnostic technique for detection of renal
allograft function and dysfunction. All the results were recorded and analyzed using SPSS
software.
Results: Mean ADC Cortex value among patients with stable renal allograft and allograft
dysfunction was 2.56 and 1.85 respectively (p- value < 0.05). Mean ADC Medulla value
among patients with stable renal allograft and allograft dysfunction was 2.51 and 1.79
respectively (p- value < 0.05). Mean R2 Cortex value among patients with stable renal
allograft and allograft dysfunction was 25.3 and 17.5 respectively (p- value < 0.05). Mean R2
Medulla value among patients with stable renal allograft and allograft dysfunction was 24.2
and 16.8 respectively (p- value < 0.05).
Conclusion:MRI is significantly helpful in assessing renal allograft dysfunction at an early
stage