European Journal of Molecular & Clinical Medicine

Abstract

Background & Method: The Study was carried out among UTI patients in Index Medical College and Associated Hospital at Khudel Village in Indore that gives healthcare to surrounding area and is used as teaching and referral hospital. The study targeted both male and female outpatients and inpatients presenting with symptoms and signs of UTI which include dysuria, polyuria, fever, nausea, and flank pain were sampled for this study. Baseline demographic data including age, sex, level of education and risk factors such as catheterization, history of UTI, also out and in patients were also collected.
Result: The 385 urine specimens processed, 112(29.0 %) showed significant growth whereas the majority of the urine samples that is 273 (71 %) showed no growth. Fresh samples were collected from patients by mid-stream catch method in sterile universal bottles (Plate 1). The assessment of associated risk factors showed gender (χ2 = 0.116, P=0.0412), age group (P=0.0120), History of UTI (χ2 =0.555, P=0.004) and symptoms of UTI (χ2 =0.895, P=0.017) were significant. Level of education (χ2 =2.742, P=0.523) and catheterization (χ2 =0.17, P=0.054) were not significant.
Conclusion: The prevalence of UTI in Index Hospital was 29.1 %. E. coli was the highest among 120 the isolates. Females had a higher (62.1 %) prevalence of UTI than males (37.9 %). Urinary tract infection was associated with the previous infection and with patients who had the history of catheterization. All isolates were sensitive to nitrofuratoin, cefotaxime and amoxicillinclavulinic acid. High resistance was observed in gentamicin, nalidixic acid, ampicillin and cotrimoxazole. In the 120 isolates were resistant for more than two antibiotics were recorded in 108 (90 %) isolates. Antibiotic susceptibility patterns of all patients with bacterial uropathogens will reduce multidrug resistance.