To findout prevalence of effect of opiumonpulmonary function tests in Western Rajasthan
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 3, Pages 5425-5430
Abstract
Introduction- Opium is one of the most common substance abuse in Asian countries.Inthis cross sectional study we clarify the effects of opium on respiratorysystem and possible
mechanism of respiratory involvement ,Method: The casecontrol study was done on two
groups of men between the ages of 30-50 years. Thecase group was of 100 opium addicts.
Thecontrol Group was of 100 healthy nonopium addicts. All of the 200 men underwent
spirometryand the results comparedwith each other. Result: In the opium addicts the mean
FVC was 3.10± 0.62L whichis significantly lower than normal value (4.2L in males).In
controls, the mean FVCwas 3.60±0.54L.P value for FVC was <0.001 which shows a
significant
resultstatistically.InourstudyopiumaddictsmeanFEV1was2.93±0.57Lwhichwasnearabout
normal than the standard normal values ruling out an obstructive defect. Meanvalues of
FEV1/ FVC was 94.0 ±0.13 %, highly suggestive of restrictive pulmonarydefects.
Conclusion: Opium abuse causes restrictive type of effect on pulmonaryfunction.
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