European Journal of Molecular & Clinical Medicine

Abstract

Background: Oral submucous fibrosis (OSF) is the oral premalignant lesion with the
highest malignant potential. Oral submucous fibrosis (OSMF) is increasingly
recognised as an Indian illness worldwide. It has one of the highest rates of malignant
transformation among potentially malignant oral lesions and diseases, making it a
source of concern for dental specialists. Understanding the precise involvement of
alkaloids and other etiological factors in pathogenesis would aid in the management and
treatment of the disease. The purpose of this study is to determine the prevalence of
OSMF in betel nut chewers of various ages who visit the Dental College and Hospital.
Materials and Methods: The study included 798 OSF patients who visited the
Department of Oral Medicine and Radiology dental outpatient clinic over the course of
18 months. In the presence of visible light, a thorough case history and clinical
examination were conducted. OSMF was diagnosed based on difficulties in opening the
mouth and the presence of blanched oral mucosa with palpable fibrous bands. Burning
sensations, salivation, tongue protrusion, tobacco intake habits, and related malignant
alterations were among the other diagnostic symptoms. The research looked at age
groups, habit length, habit frequency, and habit type. A basic correlation analysis was
carried out.