European Journal of Molecular & Clinical Medicine

Abstract

Introduction: Cardiopulmonary exercise testing (CPX) systems allow for the analysis of
exercise integrative physiology involving the pulmonary, cardiovascular, muscular, and
cellular oxidative systems. Subsequently, exercise tolerance is determined by pulmonary
gas exchange; cardiovascular performance, including the peripheral vascular tree; and
skeletal muscle metabolism.Thus, present study was commenced to
evaluateimprovement in exercise tolerance after lifestyle modification using
Cardiorespiratory Exercise Testing.
Materials and Methods: This study was conducted at a Cardiopulmonary exercise
testing unit of Grant Government Medical College & Sir J.J Group of Hospitals
(Mumbai) among 50 subjects. The subjects were told to follow a lifestyle modification
which included any form of physical activity preferably brisk walking for a duration of
30 minutes at least 5 times a week for 3 months. The paired t test was used to study the
exercise tolerance of subjects after 3 months.
Results: The VO2max, AT and METS were significantly higher in non-sedentary
subjects compared to sedentary subjects. There was significant improvement in
VO2max, AT and METS after exercise.The average VO2max after exercise was 48.38
ml/kg/min, i.e. there was 11.3 % improvement in VO2 max post exercise which was very
highly significant. The average METS after exercise was 13.81, i.e. there was 11.1%
improvement in METS post exercise which was significant. The average AT after
exercise was 67.04% of VO2max, i.e., there was 10.33 % improvement in AT post
exercise which was significant.