European Journal of Molecular & Clinical Medicine

Abstract

Background:The present study was done to determine the association of serum Ferritin
in Metabolic Syndrome as well as to determine the relation between individual
component of metabolic syndrome and number of components metabolic syndrome and
plasma ferritin.
Materials and Methods: It was a Cross-sectional study. The study was carried out at
NRI Medical College & Hospital, CHINAKAKANI, GUNTUR. The study was included
Metabolic syndrome patients diagnosed as per NCEP (National Cholesterol Education
Program) ATP III (Adult Treatment Panel III) (2001) attending the NRI medical
college and Hospital during the study period from March 2021 to March 2022. It is a
Correlational clinical single group study with 102 patients.
Results: In the present study, the mean age group of the study population was 57.38
±8.05. The majority of the study participants belonged to the 51–60 years age group, i.e.,
40.2%, followed by 36.3% in 61–70 years age group. In the present study, the majority
of the study population were male, i.e., 62.7% and females were 37.3%. In the present
study, the majority of the male and female belonged to 51- 70 years age group. In the
present study, overweight was 42%, and obese was 58%. In the present study, the
majority, i.e., 98.4%, had a waist circumference of >90 cm, and among the female
majority, i.e., 94.7% had a waist circumference of >85cm. In the present study, 87.3%
had systolic Blood pressure >130 mmHg, and 84.3% had Diastolic Blood pressure >85
mmHg. In the present study, 62.7% were Hypertensives and were taking regular
medications. 78.4% of the study population were diabetics. The mean duration of
diabetes in the present study was 2.11 ± 0.84. 18.6% had a duration of diabetes <3 years,
3-6 years in 37.3%, and 22.5% had a period being >6 years. 22.5% had 1+ urine
albumin, 2.9% with 2+ urine albumin. 74.5% didn’t show any albumin in urine
analysis. 61.8% had no sugar in the urine. Trances of sugar in urine were identified in
38.2%. Based on the ATP III criteria, metabolic syndrome was classified. 20.6% had 3
components, 28.4% had 4 components, majority i.e. 51% had 5 components identified.
In the present study, a statistically significant association was observed between
metabolic syndrome components and PPBS, Total cholesterol, Triglycerides, HDL, LDL
as the p-value calculated to be <0.05. In the present study, the mean serum ferritin
levels were 126.89 ± 51.77. There was a statistically significant association observed
between components of metabolic syndrome and serum ferritin levels as the p-value
calculated to be <0.05. In the present study, a significant relation was observed between
serum ferritin and waist circumference (r=0.33, pvalue<0.05), Total Cholesterol
(r=0.310 pvalue<0.0001), and LDL (r = 0.326; p value <0.0001).