Document Type : Research Article
Abstract
Cancer is the leading cause of death worldwide, according to the most recent WHO data report. Cancer
was responsible for almost 9.6 million deaths last year. Oncologists have found the most cases of cancer
from colorectal to skin to hepatic to prostate to stomach and from breasts. Surgery, chemotherapy, and
radiation therapy are the three main cancer treatment options now available. Chemical compounds are
typically employed in chemotherapy, a type of cancer treatment, to destroy cancer cells. A crucial aspect
of cancer treatment, chemotherapy is done either alone or in conjunction with other methods such as
surgery and radiation. It is critical. Epidermal growth factor inhibitors, anthracene derivatives, and
platinum compounds are all common anticancer drugs. Traditional chemotherapeutic treatments are
highly powerful and may kill cancer cells at very low doses, but non-specificity is still a serious problem
in clinical applications for these drugs. Various anticancer drugs delivery systems have been developed to
fix or overcome these difficulties. These limitations have been eliminated and the therapeutic efficacy of
anticancer treatments has increased with the development of nanotechnology-based drug delivery systems
(nanomedicines) in recent decades. Drug molecules in nanomedicine are either adsorbed to or
encapsulated in a nanocarrier in order to make it more effective. A nanocarrier is made up of
biodegradable and biocompatible materials and has at least one dimension smaller than 100 nm. Carbonbased
nanomaterial Graphene oxide nanosheets (GONS) were employed in this study to develop an
anticancer molecular drug delivery system.