European Journal of Molecular & Clinical Medicine

Abstract

Background:To compare the efficiency and safety of fibrin glue and suturing technique
for adherence of conjunctival limbal autograft after pterygium excision.
Materials and Methods: AProspectiveinterventional study conducted from September
2018 to December 2020 in the department of Ophthalmology at
KIMS,Narketpally.100eyesof100 patientsoperatedforprimary nasal
pterygium.Autologousconjunctival grafttakenfromthe superotemporal limbu was used
to cover the scleraafter pterygiumexcision.In50 eyes,thetransplantwasattached
tothesclerawitha fibrin tissue adhesive (BeriplastP),in 50 eyeswith10-
0Vicrylsilksutures.Outcome measures included graft position and stability,recurrence
of pterygium, Postoperativepatient discomfort(pain,watering)andbio microscopic
findings(hyperemia,edema).Patientswere followedupatleastforsixmonths.
Results: Subconjunctival haemorrhage occurred underthe graftingonepatientinFibrin
glue group.Granuloma was seen in one patient in suture group,which resolved after
suture removal. Inferior Graft dislodgement was seen in one patient in suture
group.Symptoms like pain, watering, Foreign body sensation were
significantlylessandbiomicroscopicfindingswerebetterin Fibrin glue group.Average
Surgery Cost Was Higher (<0.05)andsurgerytimewasshorter (<0.05)infibrin group.
Conclusion: Fibrin glue is a safe and effective method for attaching conjunctival limbal
autografts.Usingfibringlueforgraft fixation pterygium surgery causes significantly less
postoperative pain,watering,foreign body sensation and
shortenssurgerytimesignificantly.