Factors Affecting Seroma Formation after Modified Radical Mastectomy in Patients of Carcinoma Breast: A Prospective Study
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 3, Pages 10507-10513
AbstractIntroduction: Seroma formation is the most common complication after breast cancer
surgery, especially when axillary dissection is performed.
Aim: This study intends to find out the association between certain pre-operative, intraoperative,
and post-operative factors related to MRM and incidence of seroma
Methods: A total of 50 patients with Ca breast undergoing breast surgery were
admitted in surgical wards at tertiary carehospital.
Results: The cumulative total seroma volume collected by the end of treatment was
higher and the overall time of seroma treatment was longer in patients over the age of
60 years (60.89±9.17 vs 55.25±10.05years p<0.001) and more obese (BMI, 26.78±5.2
versus 24.86±3.91; p<0.001). Higher amount of initialdrain volume was directly related
to seroma formation.The incidence is decreased byearly initiation of arm physiotherapy
after surgery (3.21±0.91 days versus 2.08±0.76 days; p=0.0001).
Conclusion: The incidence of seroma is higher in older, obese patients and higher drain
output. The incidence is decreased by early physiotherapy. Interventions in the
operative period reduce the seroma formation.
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