European Journal of Molecular & Clinical Medicine

Abstract

Background: Urinary Tract Infection (UTI) is one of the common infections affecting people, both from the community and hospital. The causative pathogens for UTI and their drug sensitivity patterns vary from region to region. Changes in their genetic constituents with time might be the reason.
Aim: In this study, we aimed investigate the profile of common uropathogens and assess their antibiotic sensitivity patterns with commonly used drugs for UTI patients.
Materials and methods: In this study, 153 urine samples were analyzed with routine microscopy, culture and sensitivity for a period of six months at Institute of Medical Science and SUM Hospital, Bhubaneswar, Odisha. Both bacteria and fungi were used for drug sensitivity test.
Result: A total no. of 54Gram positive bacteria and 40 Gram Negative bacteria were isolated. S. aureus was the most common GPC isolated and P. aeruginosa was the most common GNB. E. coli was the second most GNB which showed resistance to Cephalosporins and Aminocoumarin group. 4 Candida species were isolated, to which Clotrimazole was the most susceptible antifungal agent. Staphylococcus sp. showed resistance to β-lactams and Macrolides group of antibiotics. Shigella sp. showed resistance to β-lactams. C. albicans was found to be the common Fungi isolated, followed by C. krusei.
Conclusion: Since the drug sensitivity pattern changes from place to place and varies from time to time. The culture sensitivity therapy should be practiced before empirical administration of antibiotics.