European Journal of Molecular & Clinical Medicine

Abstract

Introduction: Thyroid disorders are among the most common endocrine disorders, with an overall prevalence of Hypothyroidism about 10.95% in the general population. Prevalence of the Metabolic Syndrome (MetS) in the Indian population is about 31.6%, with the prevalence of 22.9% in men and 39.9% in women.
Aim: The aim of this study is to determine the prevalence of Metabolic Syndrome and its components in people with Hypothyroidism.
Materials and Methods: A total of 200Hypothyroid patients attending our out-patient  and in-patient department were consecutively enrolled for the study. Clinical data were obtained by interviewing the patients and referring to their case folders and prescriptions. The anthropometric indices were recorded. The laboratory parameters that were analyzed included fasting lipid profile, thyroid function tests, and fasting blood sugars.
Results: The patients were aged between 18 to >65years, with a mean age of 45.11 years, and the female‑to‑male ratio was 1:2.48. The overall prevalence of the  Metabolic Syndrome was significantly higher than that in the general population, as reported earlier in various studies. The most common occurring Metabolic Syndrome defining criterion was increased waist circumference, and hypertension was the least documented criterion.
Conclusion: Metabolic Syndrome occurs in approximately every second patient of hypothyroidism, and so, routine screening for components of Metabolic Syndrome may be of benefit in this group.