Recent Trends in HELLP Syndrome
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 3, Pages 10819-10825
AbstractBackground: HELLP syndrome is a serious complication in pregnancy characterized by haemolysis, elevated liver enzymes and low platelet count occurring in 0.5 to 0.9% of all pregnancies and in 10–20% of cases with severe pre-eclampsia. National Institute of Health estimates that one in every four pregnant patient develops serious complication due to HELLP syndrome which is mostly due to delayed treatment.
Aims and Objectives: This study was done to find out the prevalence of HELLP Syndrome and maternal and fetal outcomes associated with it.
Methods: The present Prospective cross sectional study was conducted in the Department of Obstetrics & Gynaecology, Maharishi Markendeshwar Institute of Medical Sciences and Research (MMIMSR), Mullana, Ambala, Haryana, India during the period from September 2020 to January 2022. 55 patients who developed HELLP syndrome or partial HELLP syndrome were studied in this study.
Results: In the present study, 1.83% of patients admitted for delivery developed HELLP syndrome. Majority of patients developed the condition by 32-36 weeks. Maternal morbidity was 34.54%. Prematurity was major fetal complication with HELPP syndrome with prevalence of 76.36%. There was no maternal death in our study.
Conclusions: HELLP Syndrome is a very severe variant and a dreadful complication of Preeclampsia and Eclampsia .Early diagnosis and appropriate intervention by termination of pregnancy to arrest further progress so as to reduce maternal and neonatal morbidity and mortality associated with this deadly disease. Timely intervention is a very important tool in bringing down the maternal and perinatal morbidity and mortality in resource poor country like India.
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