European Journal of Molecular & Clinical Medicine

Abstract

Graves’ orbitopathy/ophthalmopathy (GO) also known as thyroid eye disease (TED), dysthyroid/ thyroid associated ophthalmopathy (TAO), is an autoimmune disorder representing the commonest and most important extrathyroidal manifestation of Graves’ disease.
Materials and Methods: This is a retrospective study conducted over a period of 2 years. A total of 60 established cases of Hyperthyroidism of all Age group with either gender subjects who were diagnosed with Thyroid orbitopathy at Hospital were included in this study.
Result: A total of 60 patients were examined. Of the 60 cases analysed, female preponderance was noted and 41-60 years age group had highest incidence of thyroid orbitopathy. The most common presentation was found to be unilateral. Inferior rectus muscle was the commonest muscle involved with 48.3% followed by Medial rectus muscle 38.3%, Superior rectus muscle 23.3% and Lateral rectus muscle involved least with 11.6% in descending order. None of the patients reported loss of vision. Most common sign refractive error and least one was restrictive myopathy. The most common presenting eye sign was found to be decreased vision during the study period in patients of Hyperthyroidism which was found to be statistically significant. (p<0.05). Decreased vision was found to be the most common eye sign among all age groups which was statistically significant. (p<0.05) followed by Upper lid retraction.
Conclusions: Dry eye and increased IOP are commonly seen outcomes that should be managed diligently. This potentially sight- threatening condition is seen worldwide and has many functional and cosmetic consequences that need to be recognized. Hyperthyroidism was significantly associated with the severity.