Cholesterol Levels: Useful Predictors Of Surgical Site Infections In Emergency Laparotomy
European Journal of Molecular & Clinical Medicine,
2018, Volume 5, Issue 1, Pages 531-537
AbstractBackground and Objectives:Emergency surgeries have been found to be associated with
high rates of surgical site infections compared to elective surgeries. This study was conducted
to determine cholesterol as predictor of SSI in emergency laparotomy as to throw light on
how to minimize SSI. This study was intended to find the association between cholesterol
levels and SSI, length of hospital stay and death in emergency laparotomy.
Methodology: A prospective cohort study was conducted between April 2018 and October
2018 among 94 patients who underwent emergency laparotomy in Department of General
Surgery. Each patient will be monitored from time of admission until the time of discharge
and followed postoperatively 30 days for surgical site infection. The predictor variable is the
cholesterol. The outcome variables are surgical site infection, length of hospital stay and
death.The analysis was done to find association between this variable.
Results: During follow up of 94 patients, 29(30.8%) developed SSI and 7(8.5%) patients
died. Patients with cholesterol level 200mg/dl had 14.3% SSI. The patients with cholesterol
had increased length of stay in hospital than those with high values. The statistically
significant association between pre-op cholesterol and Death could not be made. Cholesterol
emerged significant to SSI after multivariate analysis. Cholesterol had not emerged as
significant to length of stay and death.
Conclusion: In this study, cholesterol is associated with increased risk of SSI. Association of
cholesterol with length of stay and death could not be made. Cholesterol concentration is a
better predictor of SSI.
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