European Journal of Molecular & Clinical Medicine

Abstract

Background: The fetal membranes (Amnion and Chorion) maintain their integrity
throughout the pregnancy and rupture spontaneously during the second stage of labour or the
late first stage of labour at term. Premature rupture of membranes (PROM) is defined as
rupture of amniotic membranes prior to the onset of labour. If the membranes rupture after
37 weeks its called Premature Rupture of membranes (PROM) and if before 37completed
weeks its called pre-term PROM (PPROM). The main aim of the study is to assess the
pregnancy outcome, mode of delivery, neonatal outcome and the associated factors in
patients presenting with premature rupture of membranes and comparing the outcome of term
PROM with matched group of controls with intact membranes.
Methods: 182 cases having prelabour ruptured membranes and 514 controls were were
collected with term gestational age and intact membranes for Observational Retrospective
study over a period of 8 months from 1stJune 2019 to 31 January 2020 at TMMC&RC
Moradabad UP. Progression and duration of labour, mode of delivery, latency period for
PROM, PPROM and neonatal outcome were recorded.
Results: Prematurity and prolonged rupture of membranes are two important reasons of
neonatal morbidity in PROM. Various factors like duration of labour, progression to clinical
infection and gestational age affects the fetal outcome. Rates of Caesarean section is not
increased by inducing the patients with ROM, and is comparable between patients of PPROM
and PROM
Conclusion: With proper fetomaternal monitoring and timely interventions the neonatal
outcome of premature rupture of membranes can definitely be optimized.