Genotyping of Multi Drug Resistant Tuberculosis Among the Smear Positive Pulmonary Tuberculosis Cases at a Tertiary Care Hospital
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 3, Pages 11242-11248
AbstractBackground:Mycobacterium tuberculosis was discovered by Robert Koch on March 24, 1882, and every year this day is remembered as the World Tuberculosis (TB) Day.
Objectives: To detect MDR-TB among new cases of smear positive pulmonary tuberculosis by Genotyping method.
Materials and methods: Prospective study was conducted in patients with sputum-positive pulmonary tuberculosis to detect resistance to Rifampicin and Isoniazid using Genotyping by Hain’s technique at RNTCP in IGIMS, Patna , Bihar. 78 patients were study duration of eighteen months. The data was collected after obtaining permission from Institutional Ethical Committee,
Conclusion: LPA- Hain’s technique identifies sensitivity to Rifampicin and Isoniazid in the clinical isolates and provides results in 2-3 days which in turn helps the patient to initiate early treatment and community at large to prevent the spread of MDR-TB.
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