European Journal of Molecular & Clinical Medicine

Abstract

Background: Transfusion-transmitted infections(TTIs) continue to be a threat to safe transfusion practices. A total of 30 million blood components are transfused each year in India. Blood safety thus becomes a top priority, especially with a population of around 1.23 billion and a high prevalence rate of human immunodeficiency virus (HIV) in general population in India.
Objectives: To observe any discordant results between HIV Nucleic acid Amplification Testing and HIV antibodies ELISA screening and Note relative sensitivity , specificity and diagnostic accuracy.
Materials and Methods: This is a comparative study of two different HIV diagnostic methods for sensitivity, specificity and diagnostic accuracy .It involves voluntary blood donors during period of two years. Blood Bank, IGIMS, Patna.
Conclusion: NAT could detect HIV cases in blood donor samples which were undetected by ELISA. It’s widespread use in blood banks would ensure additional layer of safety in blood transfusion.