European Journal of Molecular & Clinical Medicine

Abstract

Introduction: Thyroid disorders are among the most common endocrine disorders, with an
overall prevalence of Hypothyroidism about 10.95% in the general population. Prevalence of
the Metabolic Syndrome (MetS) in the Indian population is about 31.6%, with the prevalence
of 22.9% in men and 39.9% in women.
Aim: The aim of this study is to determine the prevalence of Metabolic Syndrome and its
components in people with Hypothyroidism.
Materials and Methods: A total of 200Hypothyroid patients attending our out-patient and
in-patient department were consecutively enrolled for the study. Clinical data were obtained
by interviewing the patients and referring to their case folders and prescriptions. The
anthropometric indices were recorded. The laboratory parameters that were analyzed included
fasting lipid profile, thyroid function tests, and fasting blood sugars.
Results: The patients were aged between 18 to >65years, with a mean age of 45.11 years,
and the female‑to‑male ratio was 1:2.48. The overall prevalence of the Metabolic Syndrome
was significantly higher than that in the general population, as reported earlier in various
studies. The most common occurring Metabolic Syndrome defining criterion was increased
waist circumference, and hypertension was the least documented criterion.
Conclusion: Metabolic Syndrome occurs in approximately every second patient of
hypothyroidism, and so, routine screening for components of Metabolic Syndrome may be of
benefit in this group.