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  2. Volume 9, Issue 4
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Online ISSN: 2515-8260

Volume9, Issue4

COMPARATIVE STUDY OF FASTING INSULIN AND HOMA-IR IN RURAL AND URBAN T2D PATIENTS

    Yogesh Kumar Rai, Pavan Gautam, Anil Kumar, Roma Goyal

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 4, Pages 285-290

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Abstract

Introduction: Insulin resistance is a feature of a number of clinical disorders, including T2D/glucose intolerance, obesity, dyslipidaemia and hypertension clustering in the so-called metabolic syndrome. Insulin resistance in skeletal muscle manifests itself primarily as a reduction in insulin-stimulated glycogen synthesis due to reduced glucose transport. 
Material and Method: A cross-sectional study was conducted on 100 subjects of type 2 diabetes having an age group of 40-70 years from urban and rural area of Meerut, U.P., India for determination of HOMA-estimated insulin resistance (HOMA-IR).
Result: We found   urban subjects had significantly higher fasting Glucose, fasting insulin and HOMA-IR values than rural subjects (p < 0.001).
Conclusion: Environmental and lifestyle changes resulting from industrialization and migration to urban environment from rural settings may be responsible to a large extent, for this epidemic of insulin resistance in Indians.
Keywords:
    Insulin resistance HOMA-IR HOMA-estimated insulin resistance
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(2022). COMPARATIVE STUDY OF FASTING INSULIN AND HOMA-IR IN RURAL AND URBAN T2D PATIENTS. European Journal of Molecular & Clinical Medicine, 9(4), 285-290.
Yogesh Kumar Rai, Pavan Gautam, Anil Kumar, Roma Goyal. "COMPARATIVE STUDY OF FASTING INSULIN AND HOMA-IR IN RURAL AND URBAN T2D PATIENTS". European Journal of Molecular & Clinical Medicine, 9, 4, 2022, 285-290.
(2022). 'COMPARATIVE STUDY OF FASTING INSULIN AND HOMA-IR IN RURAL AND URBAN T2D PATIENTS', European Journal of Molecular & Clinical Medicine, 9(4), pp. 285-290.
COMPARATIVE STUDY OF FASTING INSULIN AND HOMA-IR IN RURAL AND URBAN T2D PATIENTS. European Journal of Molecular & Clinical Medicine, 2022; 9(4): 285-290.
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