European Journal of Molecular & Clinical Medicine

Abstract

Background: Hypertensive disorders of pregnancy are one of the commonest complications of pregnancy which accounts for 12% of the maternal and perinatal mortality and morbidity and affects 3% to 10% of all pregnancies worldwide. Liver function Test (LFT) abnormalities occur in 3% of the pregnancies and probably the lesion that causes elevated serum liver enzymes. Hence, this study was done to assess and correlate liver function in the development of pregnancy induced hypertension.
Method: This Case Control study was done to correlate liver function in pregnancy induced hypertension and normal pregnancy. In the present study 140 subjects, 70 women with diagnosed pregnancy induced hypertension at gestational age of > 20 weeks as a case and 70 normotensive pregnant women at gestational age of > 20 weeks as a control were included after applying inclusion & exclusion criteria. Distribution of subject according to Gestational Hypertension is Group A, Pre-Eclampsia is Group B and Eclampsia is Group C of case and control.
 
Result: Mean Difference in SGOT, SGPT were observed in subjects with Pre-Eclampsia and Eclampsia  as compare to  Gestational Hypertension. However, no significant difference between case and control group were noted.
 
Conclusion: Our study shows that there is no significant difference in Gestational Hypertension,Pre-Eclampsiaand Eclampsia of case and control group.