CLINICAL CHARACTERISTICS AND RISK FACTORS FOR MORTALITY OF COVID-19 PATIENTS ADMITTED IN ICU
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 3, Pages 11616-11625
Abstract
Aim: To evaluate the clinical characteristics and risk factors for mortality of COVID-19 patients admitted in ICU (intensive care unit).Material and method: The present retrospective study was conducted among COVID positive patients of both genders was conducted in the department of medicine, National Capital Region Institute of Medical Sciences, Meerut from April 2021 to April 2022. Symptoms included fever, cough, dyspnea, loss of smell, loss of taste, headache, myalgia, lethargy, diarrhea, arthralgia and palpitations. Chest computed tomography (CT) imaging findings and laboratory findings were recorded. The clinical symptoms of patients in both groups of cluster and sporadic cases of COVID-19 were defined as mild, moderate, and severe. Mild cases had mild clinical symptoms with no signs of pneumonia on CT chest imaging. Patients date of admission and discharge was recorded along with the outcome i.e. whether patient was expired or survived.
Results: Fever, cough, dyspnea, loss of smell, loss of taste, headache, myalgia, lethargy, diarrhea, and arthralgia was revealed among 55%, 40%, 35%, 16%, 15%, 15%, 14%, 10%, 7% and 6% of the subjects respectively. Mortality was revealed among 18% of the subjects. Mortality due to COVID, co-morbidities and other causes like TB/HIV/Cancer/MI/COPD/CKD was reported among 5%, 11%and 2% of the subjects respectively. Univariate analysis revealed male sex, age>60 years and history of diabetes was significantly associated with mortality as p<0.05.
Conclusion: Public health interventions should aim to provide additional protection to older population or people with comorbidity such as diabetes found to be more vulnerable to severe disease progression if infected with COVID-19.
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