European Journal of Molecular & Clinical Medicine

Abstract

Background: Skin and soft tissue infections (SSTIs) are frequent forms of disease. In order
to define or improve empirical antibiotic therapy, it is necessary to generate data on the
current spectrum and susceptibility profile of bacteria associated with community-acquired
SSTIs.
Material and Methods: The clinicalsamples were obtained from 600 out-patients and the inpatientswith
community acquired skin and soft tissue infections.All clinical samples were
inoculated on the routine laboratorymedia. Antibiotic sensitivity testing was performed as per
standard guidelines.
Results:Out of 600 patients with community acquired skinand soft tissue infections, 258
(43%) were diagnosedwith abscess followed by cellulitis 145 (24.2%).Gram positive cocci
accounted for 92.27% of total isolates. Staph. aureus was the predominant pathogen
accounting for 78.75% of total isolates. Amongst the Gram negative isolates, P. aeruginosa
was predominant pathogen 7.72%.71 (19.34%)strains of MRSA were detected in the present
series.Sensitivity to other antimicrobials varied from 6.3% (penicillin G) to 97%
(clindamycin).All the strains of P. aeruginosa were found to be sensitive to the
antipseudomonal agent ceftazidime and to amikacin. The sensitivity of Pseudomonas strains
to other antimicrobials ranged from 52.8% to 97.22%.