EVALUATE AND COMPARE INTRATHECAL PLAIN LEVOBUPIVACAINE AND DEXMEDETOMIDINE AS AN ADJUVANT TO 0.5% LEVOBUPIVACAINE FOR INFRA UMBILICAL SURGERIES
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 3, Pages 11859-11869
AbstractBackground: Spinal anesthesia is a widely used technique providing faster onset with effective and uniformly distributed sensory and motor block. Due to decreased cardiovascular and central nervous system toxicity, levobupivacaine is a good alternative for spinal anesthesia.
Aim: The aim of this study is to evaluate and compare intrathecal plain levobupivacaine and Dexmedetomidine as an adjuvant to 0.5% Levobupivacaine for infra umbilical surgeries with respect to sensory and motor blockade, hemodynamic changes, and adverse effects.
Materials and methods: This is a prospective, randomized double blinded study conducted among 60 patients who were posted under elective infra-umbilical surgery. They were equally divided into Group L: They received intrathecal 0.5% Levobupivacaine 3cc Group LD: They received intrathecal 3 mcg dexmedetomidine with 0.5% Levobupivacaine.
Results: The addition of dexmedetomidine significantly prolonged the duration of sensory and motor block. The addition of dexmedetomidine significantly prolonged the time for rescue analgesia. The addition of intrathecal dexmedetomidine lead to an early onset of sensory block. The incidence of side effects was limited to the occurrence of hypotension and bradycardia in the group that received dexmedetomidine intrathecally.
Conclusion: Intrathecal dexmedetomidine as an adjuvant to spinal anaesthesia is good choice since it produces prolonged sensory and motor block.
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