European Journal of Molecular & Clinical Medicine

Abstract

Background: Dengue fever is an acute febrile illness (AFI) caused by one or more dengue viruses belonging to genus Flavivirus and transmitted by Aedes aegypti mosquito. The exact clinical and laboratory profile is crucial for early diagnosis and management of patients. Present study was aimed to study clinical outcome in adult patients with serologically proven dengue syndrome at a tertiary hospital.
Material and Methods: Present study was hospital based, observational study, conducted in patients of age > 18 years, of either gender, with acute febrile illness, with serologically proven dengue syndrome admitted in wards & ICUs.
Results: We studied 210 serologically proven dengue patients in present study. Majority of patients were from 31-40 years age group (29.05%), were male (60.48%), NS 1 Positive (81.90%). In present study, non-severe dengue (83.81%) cases were more as compared to severe Dengue fever(DHF) (16.19%). Laboratory findings such as hematocrit < 36%, leukopenia, thrombocytopenia, reactive lymphocytes, prolonged PT, prolonged APPT, SGOT>40 IU/L & SGPT >40 IU/L were common in severe dengue group as compared to non-severe dengue group & difference was statistically significant (p