European Journal of Molecular & Clinical Medicine

Abstract

Background: The silent epidemic of the twenty-first century is chronic kidney disease (CKD). According to surveys, CKD affects up to 16 percent of the adult population. It doesn't just happen in rich countries; it happens everywhere. In India, about one lakh people are diagnosed with CKD each year, necessitating a kidney transplant or lifelong dialysis. Objectives: to determine the prevalence of changes in different lipoprotein levels in non-diabetic chronic renal disease patientsMaterials and Methods: A prospective observational study was conducted in Non-diabetic CKD patients, admitted at in the Medicine ward and ICU under Medicine Department of our hospital and duration of study was 18 months which included a total of 52 patients.Results:Prevalence of dyslipidaemia was seen in almost three fourth (73.1%) of the cases with chronic kidney disease. Dyslipidaemia was seen in 64.3% cases of CKD stage III, 78.6% in stage IV and 90% in CKD stage V respectively(p<0.01). Raised cholesterol was seen in 14.3% cases of CKD stage III, 42.9% in stage IV and 80% in CKD stage V respectively(p<0.01). Conclusion: Study concluded that prevalence of dyslipidaemia in non-diabetic CKD is high. EverythreeoutoffourCKDcasesweresufferingfromdyslipidaemia,especiallyraised LDL and low HDL levels.Keywords: Lipid Profile, Non-Diabetic, Chronic kidney disease patients, dyslipidaemia