• Register
  • Login

European Journal of Molecular & Clinical Medicine

  • Home
  • Browse
    • Current Issue
    • By Issue
    • By Subject
    • Keyword Index
    • Author Index
    • Indexing Databases XML
  • Journal Info
    • About Journal
    • Aims and Scope
    • Editorial Board
    • Publication Ethics
    • Indexing and Abstracting
    • Peer Review Process
    • News
  • Guide for Authors
  • Submit Manuscript
  • Contact Us
Advanced Search

Notice

As part of Open Journals’ initiatives, we create website for scholarly open access journals. If you are responsible for this journal and would like to know more about how to use the editorial system, please visit our website at https://ejournalplus.com or
send us an email to info@ejournalplus.com

We will contact you soon

  1. Home
  2. Volume 9, Issue 4
  3. Author

Online ISSN: 2515-8260

Volume9, Issue4

Malignant Gastric Neoplasm and Its Peritoneal Metastases in Relation withCA 125 Levels: A Cross Sectional Study from a Tertiary Care Hospital of Bihar

    Major Ragini Thapa,Col Alok Sen,Major Amit Rajan,Col Ravikant Narain, Suchismita

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 4, Pages 1425-1430

  • Show Article
  • Download
  • Cite
  • Statistics
  • Share

Abstract

Gastric cancer is a malignant tumor with a fifth position amid all cancers and its mortality rate is third, globally. But the frequency varies in several parts of the world. In India, amongst men it is the fifth most common cancer and in women it is in seventh position. The objective was to study the clinical significance of serum CA125 and its relation to PD in cases of gastric cancer.Materials and Methods: An observational study with cross-sectional design was conducted by the Department of Pathology, Indira Gandhi Institute of Medical Science, Patna, Bihar, India from May 2021 to April 2022 were studied. The study included samples from 25 patients during this duration. Approval from the Institutional Ethics Committee and written informed consent from the patients was taken.All the gastrectomy specimens were sent for gross examination, staging and histopathology. The paraffin embedded tissue blocks were subsequently stained for H&E.Microsoft excel 2016 and Statistical Package for the Social Sciences (SPSS) version 18 (SPSS, Inc. Chicago, IL, USA) was used for data analysis.Results:TNM staging was done. T3 stage (16, 53.3%) comprised the major bulk of the cases followed by T2 (7, 23.3%), T4 (5, 16.7%) and T1 (2, 6.7%). Likewise, N2 nodal staging (18, 60%) was leading followed by N0 (9, 30%), N1 (2, 6.7%) and N3 (1, 3.3%). Distal metastasis was noted among 36.7% (11 cases) of the cases with liver as the most common site of metastasis followed by PD, left supraclavicular lymph node, and multiple metastases. Majority of the cases were stage IIIA (17, 56.7%) and stage IV (12, 40%).Conclusion: Early detection of peritoneal disease will help the clinicians to stratify the treatment of gastric cancers and to decide whether to go for surgical or palliative intervention.
Keywords:
    Malignant Gastric Neoplasm Peritoneal Metastases CA 125 Levels
  • PDF (175 K)
  • XML
(2022). Malignant Gastric Neoplasm and Its Peritoneal Metastases in Relation withCA 125 Levels: A Cross Sectional Study from a Tertiary Care Hospital of Bihar. European Journal of Molecular & Clinical Medicine, 9(4), 1425-1430.
Major Ragini Thapa,Col Alok Sen,Major Amit Rajan,Col Ravikant Narain, Suchismita. "Malignant Gastric Neoplasm and Its Peritoneal Metastases in Relation withCA 125 Levels: A Cross Sectional Study from a Tertiary Care Hospital of Bihar". European Journal of Molecular & Clinical Medicine, 9, 4, 2022, 1425-1430.
(2022). 'Malignant Gastric Neoplasm and Its Peritoneal Metastases in Relation withCA 125 Levels: A Cross Sectional Study from a Tertiary Care Hospital of Bihar', European Journal of Molecular & Clinical Medicine, 9(4), pp. 1425-1430.
Malignant Gastric Neoplasm and Its Peritoneal Metastases in Relation withCA 125 Levels: A Cross Sectional Study from a Tertiary Care Hospital of Bihar. European Journal of Molecular & Clinical Medicine, 2022; 9(4): 1425-1430.
  • RIS
  • EndNote
  • BibTeX
  • APA
  • MLA
  • Harvard
  • Vancouver
  • Article View: 50
  • PDF Download: 64
  • LinkedIn
  • Twitter
  • Facebook
  • Google
  • Telegram
Journal Information

Publisher:

Email:  editor.ejmcm21@gmail.com

  • Home
  • Glossary
  • News
  • Aims and Scope
  • Privacy Policy
  • Sitemap

 

For Special Issue Proposal : editor.ejmcm21@gmail.com

This journal is licensed under a Creative Commons Attribution 4.0 International (CC-BY 4.0)

Powered by eJournalPlus