TO STUDY THE CLINICAL PRESENTATION AND BIOCHEMICAL PROFILE OF PATIENT WITH MYOCARDIAL INFARCTION WITH NONOBSTRUCTIVE CORONARYARTERIES (MINOCA)
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 4, Pages 1525-1533
Abstract
Background:Studies have reported a prevalence of MINOCA of 5% to 6% of AMI cases1. The demographic and clinical characteristics of MINOCA patients differ from other patients with MICAD.Objective: To study theclinical presentation and biochemical profileof patient with Myocardial Infarction with non obstructive coronary arteries(MINOCA) in comparison to patient with Myocardial Infarction with obstructive coronary artery disease(MICAD).
Material and methods: Present study prospective comparative study was conducted in the Department of Cardiology, G.R. Medical College, Gwalior (M.P.) on an inpatient basis.Duration of study was One and half years. (Nov. 2019 to June 2021) A total of 214 patients presenting with Myocardial infarction who underwent coronary angiography were studied during this period. Our study consist of two groups of patients based on their angiographic findings that were patients with MINOCA (N=107) and patients with MI with obstructive coronary artery disease(MICAD) (N=107) which were compared based on their clinical profile and biochemical parameters.
Results: Chest pain was the most common presenting symptom among patients with MINOCA (70.1%) and Ghabrahat (83.2%) was the most common presenting symptom among patients with MICAD. Patients with MINOCA more commonly presents with atypical complaints (37.4%vs15.9%) whereas signs and symptoms of heart failure were less common among patients with MINOCA as compared to patients with MICAD.Biochemical Abnormalities like High random blood sugarlevels(8.4%vs30.8%),hypercholesterolemia(24.3%vs46.70%) and hypertriglyceridemia(8.40%vs23.40%) were less prevalent whereas reduced hemoglobin levels or Anemia (71%vs44.9%)was more prevalent among patients with MINOCA as compared to patients with MICAD.
Conclusion:Patients with MINOCA most commonly presents with chest pain. Atypical complaints was more common whereas symptoms and signs of heart failure were less common among patients with MINOCA as compared to patients with MICAD.Biochemical Abnormalities like High random blood sugar levels, hypercholesterolemia and hypertriglyceridemia were less prevalent whereas reduced hemoglobin levels (Anemia )was more prevelant among patients with MINOCA as compared to patients with MICAD.
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