European Journal of Molecular & Clinical Medicine

Abstract

The advantages of controlled hypotension to the anaesthesiologists are reduced intraoperative bleeding and hence minimization of the need for blood transfusion and a reduced duration of anaesthesia. The surgeon enjoys a dry (bloodless) operative field with minimal use of diathermy and suturing and an overall reduction in the surgical duration. Patients with subnormal or abnormal laboratory or clinical findings were excluded from the study. All patients received Tab: Alprazolam 0.5mg and Tab: Ranitidine 150mg after the Night meal on the day prior to the surgery. All patients were starved for a minimum of 8 hours prior to induction of anesthesia. The fall in MAP from basal levels to the hypotensive period was much higher in the NTG group (24.28%) than that in the ESM group (6.80%). The intra-group difference was also statistically significant.