European Journal of Molecular & Clinical Medicine

Abstract

Introduction: Upper gastrointestinal disorders are one in all the foremost commonly encountered problems in clinical practice with a high degree of morbidity and mortality. Various pathology involving the upper alimentary canal manifest with identical group of symptoms where endoscopy is performed because the initial diagnostic assay. It is straightforward safe and well tolerated procedure with direct visualisation of the pathological site and biopsy resulting in early detection of pathological changes and so helps to begin appropriate treatment.
Aims and Objectives: To determine the histopathological pattern of lesions of endoscopic biopsies of upper gastrointestinal tract.
Materials and Method: All endoscopic biopsies taken from upper gastrointestinal tract are brought in 10% buffered formalin. After fixation in formalin, the tissue was processed in automated tissue processor for dehydration, clearing, and paraffin embedding. Sections were cut in rotary microtome at 4 micrometer thickness. The section was stained for Hematoxylin and Eosin stain.
Observations: In the study conducted among all the GIT biopsies, the maximum number of biopsies were from gastric lesion with 53.84%, followed by duodenum with 36.75% and then esophageal biopsies which were 9.4%.
Conclusion:Commonestlesion was chronic gastritis. Majority of esophageal tumors were squamous cell carcinoma whereas gastric carcinoma most were adenocarcinomas.