European Journal of Molecular & Clinical Medicine

Abstract

Early oesophageal cancer has shown a good 5-year survival rate of 57%-78%. Its high mortality rate makes it a major concern. Overall survival rate is 62.5% at 1 year, 42.4% at 2 years and 30% at 5 years. The prognosis is poor in locally advanced diseases and worse in cases with distant metastasis. Squamous cell carcinomas (SCCs) and adenocarcinomas are the most common oesophageal cancers. Patients with the signs and symptoms relating to dysphagia, weight loss, and/or hematemesis were referred from various Departments. Out of all these patients, 78 patients were selected on the basis of histopathological examination (HPE) report showing the confirmed presence of carcinoma of the esophagus. All the patients with upper third growths (14 patients, 24.6%) had squamous carcinoma while 25 out of 28 patients (44%) had middle third growths had squamous carcinoma and 18 out of 36 patients (31%) with lower third growths had SCC. Adenocarcinoma was observed to be seen maximum in lower third location (85.7%). Squamous cell carcinoma was observed to be seen maximum in the middle third location (43.9%) followed by lower third location (31.6%). Adenocarcinoma was observed to be seen maximum in lower third location (85.7%). Squamous cell carcinoma was observed to be seen maximum in middle third location (43.9%) followed by lower third location (31.6%).