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  1. Home
  2. Volume 9, Issue 2
  3. Author

Online ISSN: 2515-8260

Volume9, Issue2

Evaluation of cardiac biomarkers in predicting severity of dengue fever

    Dr. Chetan Kerur, Dr. Khizerulla Sharief, Dr. Mohana , Dr. Pragalatha Kumar

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 2, Pages 2508-2513

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Abstract

Dengue virus will affect several systems of the body. Myocardial involvement may be the direct effect of the virus itself or may be due to cytokine production. Myocarditis has a varied presentation, it may be clinical or subclinical. Myocarditis can present as cardiac failure, Electrocardiogram (ECG) changes (sinus bradycardia, sinus tachycardia, T wave inversion), 2 D Echocardiography changes (reduced ejection fraction) and elevated cardiac enzymes (Troponin T, CPK, CPK-MB, LDH, N terminal-BNP). The study was approved by the institutional ethical committee. Informed written consent was obtained from the parents of each patient before enrollment. History and examination findings were recorded in a pre-structured proforma. Children with clinically diagnosed dengue fever (WHO criteria) & serologically confirmed and admitted cases between the age group of 2months to 18 years formed the study group. In 110 biomarker positive cases, 32(17.3%) had a shock, 14 (7.6%) had bleeding manifestations, 78(42.2%) cases had elevated SGOT and SGPT and PT and aPTT elevated in 84(45.4%) and 44(23.8%) cases respectively.
Keywords:
    cardiac biomarkers prediction of severity dengue fever
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(2022). Evaluation of cardiac biomarkers in predicting severity of dengue fever. European Journal of Molecular & Clinical Medicine, 9(2), 2508-2513.
Dr. Chetan Kerur, Dr. Khizerulla Sharief, Dr. Mohana , Dr. Pragalatha Kumar. "Evaluation of cardiac biomarkers in predicting severity of dengue fever". European Journal of Molecular & Clinical Medicine, 9, 2, 2022, 2508-2513.
(2022). 'Evaluation of cardiac biomarkers in predicting severity of dengue fever', European Journal of Molecular & Clinical Medicine, 9(2), pp. 2508-2513.
Evaluation of cardiac biomarkers in predicting severity of dengue fever. European Journal of Molecular & Clinical Medicine, 2022; 9(2): 2508-2513.
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