European Journal of Molecular & Clinical Medicine

Abstract

Background & Method: The aim of the study is to study the functional involvement of kidney in leprosy patients in terms of Serum Creatinine. 70 Patients of, various  age group ranging  from  5 to 65 years  were studied. out of which 53 patients were male and 17 patients were female. Creatinine reacts with picric acid in alkaline medium and form  orange-red coloured   complex formed , intensity of which is directly proportional  to creatinine in the sample and measured at 520 nm.
 
Result: In 8.57% cases serum creatinine found to be raised and all belongs to MB group. No any patients have raised  serum creatinine in PB group. Maximum number of leprosy patients were found in the age group between 31 to 40 years, in which male were 13 and female were 7, followed by the age group between 21 to 30 years, in which male were 16 and female were 3.  Minimum number of patients found in the age group between 5 to 10.
 
Conclusion: We  reached to the conclusion that in leprosy renal involvement is common and it is more in MB group as compare to PB group, in the form of serum creatinine. In 8.57% cases serum creatinine found to be raised and all belongs to MB group. No any patients have raised  serum creatinine in PB group.