European Journal of Molecular & Clinical Medicine

Abstract

Objectives: Ear is prone to various kinds of infections out of which chronic otitis media is
the most common type. Squamosal disease of chronic otitis media is associated with
cholesteatoma and is prone to secondary infections especially by aerobic bacteria. This study
was done to assess culture and sensitivity of preoperative aural swab and swab from purulent
material from mastoid with cholesteatoma obtained intraoperatively during surgery.
Comparative study has been made.
Methods: 100 Cases of chronic superlative otitis media of squamosal type with clinical
diagnosis of cholesteatoma who were admitted and underwent mastoidectomy operation in
tertiary ENT care centre during the period from November 2018-September 2020 were
studied. Pus obtained during aural toilet was sent for bacteriological and antibiotic sensitivity
studies and intraoperatively obtained cholesteatoma matrix sent for bacteriological study.
Results: Polymicrobial floras were observed both in pre-operative and intra-operative
cultures. Staphylococcus aureus and Pseudomonas aeruginosa were the most common
pathogens identified.
Conclusion: This study might have a role in facilitating use of culture guided antibiotic
therapy to improve postoperative outcome and also to prevent recurrences, eventually helping
in giving disease free ear to the patient.