European Journal of Molecular & Clinical Medicine

Abstract

Introduction: Acute lung injury and its more severe form, acute respiratory distress syndrome (ARDS), cause respiratory failure, the most common organ failure leading to intensive care. Airway pressure release ventilation (APRV, also known as Bi-Level and Bi-phasic) is a time-cycled, time triggered, pressure-targeted form of ventilatory support. Specifically, conventional pressure-targeted SIMV uses a "physiological" inspiratory time with I:E ratio less than 1:1.
Aim: To compare Airway Pressure Release Ventilation (APRV) mode with Synchronized Intermittent Mandatory Ventilation (SIMV) mode in Acute Respiratory Distress Syndrome (ARDS) patients.
Method: Present study was carried out for one year duration from 1 November 2015 to 31 October 2016 on patients who were pre-diagnosed as ARDS, who were  on mechanical ventilation in the Intensive Care Unit of MBS hospital attached to Govt. Medical College, Kota. Results: Mortality rate in Group I was 55% whereas the same in Group II was 60%.