European Journal of Molecular & Clinical Medicine

Abstract

Background & Method: The aim of the study is to study the Complications and Associated Risk Factors of Dengue in Children. Dengue sero positive patients are selected and examined clinically for hepatomegaly and jaundice and subjected to complete blood count, liver function tests, ultrasound abdomen, PT, APTT, Widal, HBsAg, HCV and analysed. Bilirubin reacts with sulphanilic acid to produce an azo compound, the colour of which could be measured at 546 nm and this gives an estimate of concentration of bilirubin.
 
Result: In this study, Dengue has affected male and female children almost equally. Thrombocytopenia has occurred in 74% of patients with probable dengue, 98% with warning signs and 100% in severe dengue.
 
Conclusion: In developing country like India, incidence of dengue outbreaks is increasing. Hepatic involvement of varying degrees has been reported. As hepatic dysfunction in dengue is transient and reversible, early identification of the same would help to reduce life threatening complications. Dengue is a self-limiting disease that is caused by viral infection. Dengue must be well treated even if patients are asymptomatic. Complications of Dengue can be manifested in many organs, including neurological, Gastrointestinal, Hematology, Cardiac & Renal systems