European Journal of Molecular & Clinical Medicine

Abstract

The most common target organs where fine needle aspiration cytology (FNAC) is performed are salivary glands because of their superficial location and easy accessibility introduced into a mass, cellular material is aspirated, and a cytological diagnosis is rendered as It separates reactive and inflammatory processes that do not require surgical intervention from neoplasia and benign from malignant tumors.
OBJECTIVES:
To study the cytomorphological features in lesions of salivary glands. To correlate the cytological features with histopathological features wherever possible. To evaluate the diagnostic utility of fine needle aspiration cytology of lesions in the salivary glands.
METHODOLOGY:
A total of 120 patients with salivary gland diseases were included in the study. This is a retrospective cohort study, undertaken in the Department of Pathology, Fathima Institute of Medical sciences, Kadapa during the period of Jan 2016 to Feb 2020. The sensitivity, specificity and overall diagnostic accuracy was calculated using Galen and Gambino method.
RESULTS:
Our study included 120 patients with salivary gland diseases. Age group of patients with salivary gland diseases ranged from 10 years to 88 years with the mean age of 44.62 years. Majority of the patients belonged to the age group of 31-40 years (35%). Male to Female ratio was 1.25: 1. Among the 120 patients, most common non neoplastic 67.52%, benign 71.79% and malignant 28.20% lesions.
CONCLUSION:
FNAC of salivary gland is a reliable and sensitive diagnostic method for diagnosis of salivary gland lesions. It not only provides preoperative diagnosis for management but also can prevent unnecessary surgeries.