Document Type : Research Article
Abstract
Aim: The purpose of the present research was evaluating the effects of magnesium sulphate on arterial blood pressure in cases of elective laparoscopic surgeries.
Methodology: 200 patients who underwent laparoscopic abdominal surgery were randomly divided in to two groups, group A and group B. Group A received magnesium sulphate 50 mg/kg diluted in normal saline to total volume of 20 ml at 240 ml/hour over 5 minutes. The control group (group B) received same amount of normal saline (20 ml).
Results: The baseline characteristics of the magnesium sulphate and Control groups were comparable and there was no significant difference between the groups. Systolic and Diastolic BP were higher in Control group than magnesium group. There was no significant difference in sedation levels in both groups.
Conclusion: In our study, we conclude that IV magnesium sulphate, when given before pneumoperitoneum attenuates arterial pressure increase during elective laparoscopic abdominal surgeries. This attenuation is apparently related to reductions in the release of catecholamine, vasopressin or both by magnesium sulphate.
)