ASSESSMENT OF THYROID CANCER IN CHILDREN
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 6, Pages 45-50
AbstractBackground: Pediatric thyroid cancer is a rare entity that is treatable with an excellent prognosis. The present study was conducted to assess thyroid cancer in children.
Materials & Methods: 56 pediatric patients of suspected nodules of both genders were included. Serum TSH was measured in all children referred for suspected thyroid nodules. Hypothyrotropinemic patients underwent 123I scintigraphy to assess for nodule autonomy. Thyroid ultrasonography was performed with a 5 to 18 MHz transducer.
Results: Out of 56 patients, boys were 30 and girls were 26. The number of nodules ≥ 1 cm per patient was 1 seen in 46, 2 in 7, 3 in 2 and 5 in 1 patient. Lobe involved were bilateral in 10, isthmus in 4, right lobe in 24 and left lobe in 20 patients. The difference was significant (P< 0.05). Cystic content was 0% (solid) in 60%, <25% in 25%, 25-50% in 10%, 50-75% in 3% and >75% in 2%. Calcifications was present in 84% and absent in 16%. Nonspecific lymph node enlargement was present in 55% and absent in 45%. The difference was significant (P< 0.05).
Conclusion: Pediatric patients with discrete thyroid nodules ≥ 1 cm in maximum diameter have greater relative cancer risk.
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