• Register
  • Login

European Journal of Molecular & Clinical Medicine

  • Home
  • Browse
    • Current Issue
    • By Issue
    • By Subject
    • Keyword Index
    • Author Index
    • Indexing Databases XML
  • Journal Info
    • About Journal
    • Aims and Scope
    • Editorial Board
    • Publication Ethics
    • Indexing and Abstracting
    • Peer Review Process
    • News
  • Guide for Authors
  • Submit Manuscript
  • Contact Us
Advanced Search

Notice

As part of Open Journals’ initiatives, we create website for scholarly open access journals. If you are responsible for this journal and would like to know more about how to use the editorial system, please visit our website at https://ejournalplus.com or
send us an email to info@ejournalplus.com

We will contact you soon

  1. Home
  2. Volume 9, Issue 5
  3. Author

Online ISSN: 2515-8260

Volume9, Issue5

Significant endoscopic findings and the probable associated factors in dyspeptic patients: A cross-sectional study conducted in a tertiary care hospital, rural Mandya

    Dr. Yamuna VS, Dr. Sachin K, Dr. Selva Rani, Dr. Veena Ghanteppagol, Dr. Ullas Mahesh

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 5, Pages 382-390

  • Show Article
  • Download
  • Cite
  • Statistics
  • Share

Abstract

Introduction: Dyspepsia is the most common gastrointestinal problem. Majority of dyspepsia is functional dyspepsia. Due to the high prevalence of dyspepsia, inappropriate use of upper GI Endoscopy can lead to unnecessary costs, risk of complications, and associated with reduced diagnostic yield.
Objectives:

To determine the prevalence of significant endoscopic finding (SEF) and H.Pylori in dyspeptic patients.
To determine the response of dyspeptic patients to PPIs and H.pylori eradication therapy.
To assess the factors predicting SEF in dyspeptic patients.

Materials and Methods: This was a cross-sectional study conducted for a period of 18 months among 100 patients with dyspepsia at department of general surgery of a tertiary care hospital. Data was collected using a semi-structured questionnaire by interview technique. The study subjects were subjected to upper gastro-intestinal endoscopy during which biopsies were taken and sent for routine histopathology examination. Descriptive and inferential statistics has been carried out in the present study. A P value < 0.05 was considered statistically significant.
Results: The mean age of the study subjects was 45.13±14.06 years. Pain abdomen was the commonest (82.0%) alarm symptom of dyspepsia and 64.0% of those with dyspepsia were smokers and 61.0% were alcoholics. Overall prevalence of significant endoscopic finding (SEF) was 36.0% and duodenal ulcer (22.0%) was the commonest of all. 71.0% revealed H.pylori infection and at least 90.0% responded well to proton pump inhibitors (PPIs) and triple drug therapy. Among the different factors, bloating or belching was found to be significantly associated with the SEF.
Conclusion: The prevalence of SEF was 36.0% and H.pylori was 71.0%. Most of them i.e. 90.0% responded both clinically and microbiologically to the treatment and bloating or belching was a significant alarm symptom associated with SEF. A trial of proton pump inhibitors (PPIs) and triple drug therapy can be considered before subjecting the patients to the invasive procedure of endoscopy.
Keywords:
    Dyspepsia significant endoscopic finding H.pylori Smoking Alcohol consumption NSAIDs corticosteroid H.pylori eradication therapy
  • PDF (348 K)
  • XML
(2022). Significant endoscopic findings and the probable associated factors in dyspeptic patients: A cross-sectional study conducted in a tertiary care hospital, rural Mandya. European Journal of Molecular & Clinical Medicine, 9(5), 382-390.
Dr. Yamuna VS, Dr. Sachin K, Dr. Selva Rani, Dr. Veena Ghanteppagol, Dr. Ullas Mahesh. "Significant endoscopic findings and the probable associated factors in dyspeptic patients: A cross-sectional study conducted in a tertiary care hospital, rural Mandya". European Journal of Molecular & Clinical Medicine, 9, 5, 2022, 382-390.
(2022). 'Significant endoscopic findings and the probable associated factors in dyspeptic patients: A cross-sectional study conducted in a tertiary care hospital, rural Mandya', European Journal of Molecular & Clinical Medicine, 9(5), pp. 382-390.
Significant endoscopic findings and the probable associated factors in dyspeptic patients: A cross-sectional study conducted in a tertiary care hospital, rural Mandya. European Journal of Molecular & Clinical Medicine, 2022; 9(5): 382-390.
  • RIS
  • EndNote
  • BibTeX
  • APA
  • MLA
  • Harvard
  • Vancouver
  • Article View: 32
  • PDF Download: 40
  • LinkedIn
  • Twitter
  • Facebook
  • Google
  • Telegram
Journal Information

Publisher:

Email:  editor.ejmcm21@gmail.com

  • Home
  • Glossary
  • News
  • Aims and Scope
  • Privacy Policy
  • Sitemap

 

For Special Issue Proposal : editor.ejmcm21@gmail.com

This journal is licensed under a Creative Commons Attribution 4.0 International (CC-BY 4.0)

Powered by eJournalPlus